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J J   26 Mar 2019

Amino Acid In-Depth Look: L-SERINE


You may have heard of or seen L-Serine powder before at your local supplement store and wondered what it is and what does it do?  Well L-Serine has been around for a long time however it is only now that it is being discovered as having many potential benefits for us. There is some great research currently being done which is giving us insight into L-Serine and how it interacts with the human body.

L-Serine is a naturally occurring amino acid. It is essential for the synthesis of Phosphatidylserine, purines, pyrimidines and other amino acids in the human body. It is currently being investigated for its Neuroprotective potential, Alzheimer’s prevention ability, sleep improvements and many more benefits.

Neuroprotective Potential: L-Serine is showing great promise as a neuroprotective agent. Studies on animals have shown up to an 85% slowing of neurodegeneration and a human clinical trial has shown that it can slow the functional decline in ALS (Amyotrophic lateral sclerosis) patients. Further support of L-Serine as a neuroprotective agent can be seen in the Okinawa Japan, in this city the average person consumes a large about of L-serine in their natural diet. The L-serine is found in their regular foods such as tofu, edamame, seaweed and pork. The people of Okinawa are known for their longevity, aging population and neurological health, with their life expectancy being higher than that of the average population in Japan (1)

L-Serine and Sleep: A 2014 study found that ingestion of 3g L-Serine 30 min before going to bed improved sleep quality. The ability to fall asleep and the ability to stay asleep was improved in the patients who took the L-Serine before bed. Patients who took L-Serine before sleep also rated their overall sleep quality higher than the patients who took the placebo (2).

L-serine research is ongoing but the early indications are looking very promising. If you are interest in investigating L-serine further and getting more information, see the article at for a great summary of all the benefits it is currently being investigated for.

CYOS blog content is for informational and educational purposes only, and should not be considered medical advice, diagnosis or treatment recommendations. Always consult with your doctor or medical professional before using any dietary supplements or if you suspect you have any medical concerns or issues.




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