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J J   08 Jan 2020

Increase Absorption With BioPerine


What is BioPerine?

BioPerine is a superior, patent, black pepper concentrate. Black pepper is commonly used as a spice or flavour enhancer in food, but it’s known to benefit supplement formulas by boosting ingredient absorption or bioavailability. It works by inhibiting glucuronidation, a process where enzymes in the body break down much of an ingredient’s components into forms meant for excretion. 


While glucuronidation helps reduce the likelihood of having excess levels of drugs and supplements circulating inside the body, it could also drastically reduce nutrient uptake. Reducing nutrient uptake can weaken the effects of ingredients in supplements. Adding black pepper allows companies to add the minimum effective dose and still get a similar absorption rate as if they used heavy dosages.


What makes BioPerine better than plain black pepper is how it’s standardised for piperine, black pepper’s active component. Piperine is the compound responsible for what makes black pepper really good at boosting absorption.


With BioPerine, glucuronidation is almost skipped or bypassed, allowing supplements to be absorbed in a more efficient manner. 


Some of the Supplements BioPerine increases bioavailability include:


Some studies also show that BioPerine also positively affects performance enhancing ingredients like creatine, beta alanine, citrulline, and stimulants like caffeine.

Performance and Health Benefits of Taking BioPerine

1. Enhanced nutrient absorption

The primary function of BioPerine is its ability to vastly improve the absorption rates of various nutrients in supplements. Combining BioPerine with performance formulas allows supplement companies to use high quality ingredients at a medium dosage and still give the same results with formulas that make use of heavy dosages, yet omit the use of any bioavailability enhancers.

While BioPerine works with almost every ingredient out there, it’s most popularly paired with turmeric or curcumin supplements. Turmeric has a really low absorption rate, but studies show combining black pepper with turmeric significantly boosts bioavailability. [1]

2. Better metabolism

A little known side benefit to taking BioPerine is how it can help the person burn more fat naturally. The boost in metabolism is done so indirectly, as it occurs because of BioPerine’s bioavailability improving effect which causes the body to increase in temperature. This increase in body temperature (that isn’t caused by an infection) is referred to as thermogenesis, a process that forces the body to burn more calories for a limited time. [2]

3. Mood enhancement

The active compound in BioPerine is piperine. In fact, it’s standardised to no less than 95% piperine. This compound mainly affects enzymes that break down nutrients, but it could also touch on neurotransmitters involved in mood, such as dopamine and serotonin. These two neurotransmitters are responsible for giving us a good or bad mood. When you’re low on them, you feel down or angry. When you have high levels, which piperine can help with, you feel positive and motivated. [3]

4. Mental benefits

Some research shows that piperine can significantly impact the way the brain works, specifically when it comes to cognition and memory. Piperine can improve the production of brain chemicals responsible for memory retention, attention span, and reasoning skills. This makes BioPerine a little bit of a nootropic. If you pair it with a powerful brain supplement, it could just give your brain the boost it needs whether you’re studying or working on a complicated company report. [4]

5. Anti-inflammatory properties

Chronic inflammation is thought to be the leading cause of almost every disease. Chronic inflammation is linked to heart disease, strokes, autoimmune disorders, arthritis, etc. Some studies indicate piperine as an anti-inflammatory compound and is known to specifically help with reducing symptoms of arthritis. [5]



BioPerine is the name of a patented brand of black pepper concentrate. This brand is specifically standardized for black pepper’s active compound Piperine. Piperine is responsible for the many benefits of black pepper in supplements and formulas. Multiple studies have shown that supplementing with BioPerine can have benefits for nutrient absorption, anti-inflammation, memory and cognition, weight loss, and an overall positive mood. 


BioPerine is available is powder form.



  1. Zhang Y, Henning SM, Lee RP, et al. Turmeric and black pepper spices decrease lipid peroxidation in meat patties during cooking. Int J Food Sci Nutr. 2015;66(3):260–265. doi:10.3109/09637486.2014.1000837
  2. Shah SS, Shah GB, Singh SD, et al. Effect of piperine in the regulation of obesity-induced dyslipidemia in high-fat diet rats. Indian J Pharmacol. 2011;43(3):296–299. doi:10.4103/0253-7613.81516
  3. Gomez-Pinilla F, Nguyen TT. Natural mood foods: the actions of polyphenols against psychiatric and cognitive disorders. Nutr Neurosci. 2012;15(3):127–133. doi:10.1179/1476830511Y.0000000035
  4. Iqbal G, Iqbal A, Mahboob A, Farhat SM, Ahmed T. Memory Enhancing Effect of Black Pepper in the AlCl3 Induced Neurotoxicity Mouse Model is Mediated Through Its Active Component Chavicine. Curr Pharm Biotechnol. 2016;17(11):962-73.
  5. Bang JS, Oh DH, Choi HM, et al. Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1beta-stimulated fibroblast-like synoviocytes and in rat arthritis models. Arthritis Res Ther. 2009;11(2):R49. doi:10.1186/ar2662
CYOS blog content is for informational and educational purposes only, and should not be considered medical advice, diagnosis or treatment recommendations. Always consult with your doctor or medical professional before using any dietary supplements or if you suspect you have any medical concerns or issues.




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